Mexican trafficking organizations dominate the drug trade in Wyoming. These groups traffic marijuana, methamphetamine and cocaine. While cocaine is readily available the use of the drug has decreased. it can be found mostly in Laramie and Cheyenne. While crack is available in some places in Wisconsin, it is difficult to obtain.

Heroin is not a threat to Wisconsin. It is available but its use and distribution is not problematic. Methamphetamine has however posed a problem in recent years. Law enforcement agencies are particularly concerned about the abuse of meth because users often tend to get violent, neglect their children and abuse their spouses the output of local labs has declined.

The club drugs most available in Wyoming are ecstasy, GHB, magic mushrooms and LSD. There are used primarily in or around college campuses. Marijuana is readily available and one of the most abused drugs in Wyoming. It is imported from Mexico and also Canada. There are also indoor and outdoor cultivation operations within the state.

Valium, Percodan, Dilaudid and Percocet are the prescription drugs abuse most in Wisconsin. They are obtained via doctor shopping and illegally purchased from healthcare professionals.